Key result
Reductions in heart rate variability reflect autonomic nervous system alterations in depression and may serve as a useful endophenotype for assessing psychological and physical comorbidities.
Design
Review
Authors
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May support HRV assessment in depression comorbidities; leaves open prospective validation before clinical use.
Heart rate variability may serve as a valuable biomarker for assessing autonomic dysfunction and evaluating the efficacy of therapies in depression and related psychosomatic conditions.
Sgoifo et al. (2015) conducted a review in Depression. Reductions in heart rate variability reflect autonomic nervous system alterations in depression and may serve as a useful endophenotype for assessing psychological and physical comorbidities.
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