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Abstract Background Three-dimensional (3D) motion analysis is an advanced tool used to quantify movement patterns in adults with chronic stroke and children with cerebral palsy. However, gold-standard marker-based systems have limitations for implementation in clinical settings. Markerless motion capture using Theia3D may provide a more accessible and clinically feasible alternative, but its accuracy is unknown in clinical populations. The purpose of this study was to quantify kinematic differences between marker-based and markerless motion capture systems in individuals with gait impairments. Methods Three adults with chronic stroke and three children with cerebral palsy completed overground walking trials while marker-based and markerless motion capture data were synchronously recorded. Time-series waveforms of 3D ankle, knee, hip, and trunk angles were stride normalized and compared. Root mean squared error, maximum peak, minimum peak, and range of motion were used to assess discrete point differences. Pearson's correlation and coefficient of multiple correlation were computed to assess similarity between the time series joint angle waveforms from both systems. Results This study demonstrates that markerless motion capture using Theia3D produces good agreement with marker-based in the measurement of gait kinematics at most joints and anatomical planes in individuals with chronic stroke and cerebral palsy. Conclusions This is the first investigation to study the feasibility of Theia3D markerless motion capture for use in chronic stroke and cerebral palsy gait analysis. Our results indicate that markerless motion capture may be an acceptable tool to measure gait kinematics in clinical populations to provide clinicians with objective movement assessment data.
Steffensen et al. (Wed,) studied this question.