Key result
Neo-adjuvant chemotherapy induces systemic organ changes requiring tailored anesthesia during major oncological surgery.
Why the study?
To review the effects of neo-adjuvant chemotherapy on main organ systems, subsequent anaesthetic implications in major oncological surgery, and evidence-based solutions.
What are the anesthetic implications and organ system effects of neo-adjuvant chemotherapy in patients undergoing major oncological surgery?
What are the anesthetic implications and organ system effects of neo-adjuvant chemotherapy in patients undergoing major oncological surgery?
This narrative review summarizes the systemic effects of neo-adjuvant chemotherapy and provides evidence-based multidisciplinary strategies for anesthetic management during major oncological surgery.
Answers are grounded in this paper and cite their sources.
Requires consideration of neo-adjuvant chemotherapy effects in anesthetic planning; leaves open prospective validation of tailored strategies.
Objective: To review and summarise the current literature describing the effects of neo-adjuvant chemotherapy on the body’s main organ systems and the subsequent anaesthetic implications of these changes in patients undergoing major oncological surgery. To offer a summary of evidence-based multidisciplinary-led solutions in order to mitigate these impacts.
No takes yet. Share an insight, caveat, or question.
Barnes et al. (2021) studied this question. Neo-adjuvant chemotherapy induces systemic organ changes that necessitate tailored anesthetic strategies and multidisciplinary management during major oncological surgery.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: