Tubular Reabsorption of Sodium Ion: Influence of Factors Other Than Aldosterone and Glomerular Filtration Rate

Physical FactorsIN recent years numerous investigations have demonstrated effects on urinary sodium excretion of so-called "physical factors" that are independent of glomerular filtration rate and aldosterone activity. These physical factors are considered here under three headings: renal hemodynamic factors; compositional factors; and neural and systemic hemodynamic factors.Renal Hemodynamic Factor n Sodum ReabsorptionEffect of renal arterial pressure. In reference to the kidney, Cushny,1 in 1917, stated that "no other gland is known to respond so readily to changes in blood pressure..." Eight years later Starling and Verney2 gave their opinion that "blood pressure as a factor in the . . .