Key result
Arterial hypertension (OR 4.90) and older age increased the risk of intracranial hemorrhage after AMI thrombolysis, whereas beta-blockers (OR 0.49) and ACE inhibitors (OR 0.48) reduced the risk.
Why the study?
What are the predisposing factors for intracranial hemorrhage and subsequent mortality in patients with acute myocardial infarction treated with thrombolysis?
Observational (n=17,111)
Yes
What are the predisposing factors for intracranial hemorrhage and subsequent mortality in patients with acute myocardial infarction treated with thrombolysis?
In patients with AMI treated with thrombolysis, age and hypertension increase the risk of intracranial hemorrhage and mortality, whereas the use of beta-blockers and ACE inhibitors is associated with a reduction in both incidence and mortality.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Ruiz-Bailén et al. (2005) conducted an observational in Acute myocardial infarction (AMI) treated with thrombolysis (n=17,111). Risk factors (age, hypertension, smoking, beta-blockers, ACE inhibitors) was evaluated on Development of intracranial hemorrhage (ICH) and mortality. Arterial hypertension (OR 4.90) and older age increased the risk of intracranial hemorrhage after AMI thrombolysis, whereas beta-blockers (OR 0.49) and ACE inhibitors (OR 0.48) reduced the risk.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: