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August 17, 2019340 citationsOpen Access

ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction).

VFValentı́n FusterSSSidney C. SmithJAJoseph S. Alpert

Key Result

The ACC/AHA guidelines provide comprehensive, evidence-based recommendations for the diagnosis, management, and prevention of ST-elevation myocardial infarction.

Key Points

  • To provide updated, evidence-based clinical practice recommendations for diagnosing and managing patients presenting with acute ST-elevation myocardial infarction.
  • Convened an expert ACC/AHA Task Force committee to systematically revise the 1990, 1996, and 1999 acute myocardial infarction guidelines.
  • Synthesized clinical evidence on acute coronary syndrome mechanisms, electrocardiogram stratification, and cardiac biomarkers of necrosis.
  • Established 12-lead electrocardiogram evaluation as the core initial method to stratify acute coronary syndrome into ST-elevation and non-ST-elevation presentations.
  • Standardized diagnostic criteria separating unstable angina from non-Q-wave myocardial infarction based on detectable circulating biomarkers of myocardial necrosis.

Structured PICO

P
Population
Patients with ST-elevation myocardial infarction (STEMI) / acute myocardial infarction (AMI)
I
Intervention
Guideline-directed management

This document provides the ACC/AHA guidelines for the management of patients presenting with ST-elevation myocardial infarction.

Limitations

  • Variations in inclusion and exclusion criteria from one randomized trial to another impose some limitation on the generalizability of their findings.

Abstract

"The process of guideline development for management of patients with acute myocardial infarction (AMI) has undergone substantial evolution since the inaugural publication entitled “Guidelines for the Early Management of Patients with Acute Myocardial Infarction” in 1990 under the auspices of the ACC/AHA Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures (Chairman, Dr. Rolf Gunnar; Figure 1) (1). Subsequently, the ACC/AHA Task Force on Practice Guidelines convened a committee (Chairman, Dr. Thomas J. Ryan) in 1994 to revise the 1990 guidelines. In the 1996 guideline publication, “ACC/AHA Guidelines for the Management of Patients with Acute Myocardial Infarction,” the term acute coronary syndrome was used, reflecting the emerging overarching concept that disruption of a vulnerable or high-risk plaque causes an episode of ischemic discomfort (2). Emphasis was placed on the 12-lead electrocardiogram (ECG) that was used to categorize patients into 2 broad cohorts: those presenting with ST elevation and those presenting without ST elevation (ultimately diagnosed as unstable angina or non–Q-wave myocardial infarction (MI) depending on whether a biomarker of necrosis was detected in the patient’s blood). The 1996 guidelines discussed the management of both the ST-elevation and non–ST-elevation presentations of the acute coronary syndromes. The same approach was taken in the 1999 update of the guideline (also chaired by Dr. Ryan) that was posted as an electronic update on the ACC and AHAWorld Wide Web sites (3)."

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Cite This Study

Fuster et al. (2019) conducted a review in ST-elevation myocardial infarction (STEMI). Guideline-directed medical therapy and interventions was evaluated. The ACC/AHA guidelines provide comprehensive, evidence-based recommendations for the diagnosis, management, and prevention of ST-elevation myocardial infarction.

synapsesocial.com/papers/6a155bb8a4734e8e604e3c2bhttps://doi.org/10.17615/5fwy-yt51
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction - Executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction)2019 · 188 citations
  2. 2Highlights From the 2013 ACCF / AHA Guidelines for the Management of ST ‐Elevation Myocardial Infarction and Beyond2014 · 20 citations
  3. 3ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction)2019 · 39 citations
  4. 4ST Elevation Myocardial Infarction Guidelines Today: A Systematic Review Exploring Updated ACC/AHA STEMI Guidelines and Their Applications2009 · 12 citations
  5. 5Synopsis and Review of the American College of Cardiology Foundation/American Heart Association 2013 ST-Elevation Myocardial Infarction Guideline2014 · 2 citations