Key result
Catheter ablation achieves comparable one-year arrhythmia freedom after prior mitral versus tricuspid valve surgery.
Why the study?
Data comparing the electrophysiological characteristics and catheter ablation results of macro-reentrant atrial tachycardia after tricuspid versus mitral valve surgery are limited.
Does the effectiveness of catheter ablation for macro-reentrant atrial tachycardia differ between patients with prior tricuspid versus mitral valve surgery?
Cohort (n=48)
No
Does the effectiveness of catheter ablation for macro-reentrant atrial tachycardia differ between patients with prior tricuspid versus mitral valve surgery?
Absolute Event Rate: 76.7% vs 72.2%
p-value: p=0.70
Catheter ablation of macro-reentrant atrial tachycardia after tricuspid or mitral valve surgery has comparable acute and mid-term effectiveness, despite significant differences in the types of MATs between the two groups.
May support ablation similarly after mitral or tricuspid valve surgery; hypothesis-generating and requires randomized confirmation.
BACKGROUND: Macro-reentrant atrial tachycardias (MATs) are a common complication after cardiac valve surgery. The MAT types and the effectiveness of MAT ablation might differ after different valve surgery. Data comparing the electrophysiological characteristics and the ablation results of MAT post-tricuspid or mitral valve surgery are limited. METHODS: Forty-eight patients (29 males, age 56.1 ± 13.3 years) with MAT after valve surgery were assigned to tricuspid valve (TV) group (n = 18) and mitral valve (MV) group (n = 30). MATs were mapped and ablated guided by a three-dimensional navigation system. The one-year clinical effectiveness was compared in two groups. RESULTS: Nineteen MATs were documented in TV group, including 16 cavo-tricuspid isthmus (CTI)-dependent AFL and 3 other MATs at right atrial (RA) free wall, RA septum and left atrial (LA) roof. Thirty-nine MATs were identified in MV group, including15 CTI-dependent AFL, 8 RA free wall scar-related, 2 RA septum scar-related, 8 peri-mitral flutter, 3 LA roof-dependent, 2 LA anterior scar-related, and 1 right pulmonary vein-related MAT. Compared with TV group, MV group had significantly lower prevalence of CTI-dependent AFL (38.5% vs. 84.2%), higher prevalence of left atrial MAT (35.9 vs.5.3%) and higher proportion of patients with left atrial MAT (40 vs. 5.6%), P = 0.02, 0.01 and 0.01, respectively. The acute success rate of MAT ablation (100 vs. 93.3%) and the one-year freedom from atrial tachy-arrhythmias (72.2 vs. 76.5%) was comparable in TV and MV group. No predictor for recurrence was identified. CONCLUSION: Although the types of MATs differed significantly in patients with prior TV or MV surgery, the acute and mid-term effectiveness of MAT ablation was comparable in two groups. TRIAL REGISTRATION: This study was registered as a part of EARLY-MYO-AF clinical trial at the website ClinicalTrials. gov (NCT04512222).
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Wang et al. (2021) conducted a cohort in Macro-reentrant atrial tachycardia after cardiac valve surgery (n=48). Catheter ablation vs. Tricuspid valve surgery group was evaluated on One-year freedom from atrial tachy-arrhythmias (p=0.70). Catheter ablation of macro-reentrant atrial tachycardia achieved comparable one-year freedom from atrial tachy-arrhythmias in patients with prior mitral (76.7%) versus tricuspid (72.2%) valve surgery.
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