Key result
CABG surgery was associated with an initial increased risk of depression at 1-2 weeks (RR 1.27; 95% CI 1.01-1.61), followed by a significantly decreased risk at >6 months (RR 0.68; 95% CI 0.58-0.79).
Why the study?
Does the risk of depression change after coronary artery bypass graft (CABG) surgery compared to preoperative levels?
Meta-Analysis
Does the risk of depression change after coronary artery bypass graft (CABG) surgery compared to preoperative levels?
Effect estimate: RR 0.68 (95% CI 0.58-0.79)
The risk of depression initially increases 1-2 weeks post-CABG but significantly decreases from 2 weeks to >6 months postoperatively, though many patients do not achieve full remission.
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Early post-CABG depression monitoring is warranted with later risk reduction expected; extends meta-analytic evidence on temporal mental health trajectories.
Ravven et al. (2013) conducted a meta-analysis in Depression and coronary artery disease. Coronary artery bypass graft (CABG) surgery vs. Preoperative baseline was evaluated on Risk of depression at late (>6 months) postoperative time point (RR 0.68, 95% CI 0.58-0.79). CABG surgery was associated with an initial increased risk of depression at 1-2 weeks (RR 1.27; 95% CI 1.01-1.61), followed by a significantly decreased risk at >6 months (RR 0.68; 95% CI 0.58-0.79).
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