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July 14, 2022Frontiers in PhysiologyOpen Access

The Harm of Metabolically Healthy Obese and the Effect of Exercise on Their Health Promotion

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Key result

Exercise corrects abnormal metabolic pathways in metabolically healthy obesity to reduce related health hazards.

Why the study?

Metabolically healthy obesity is harmful to health, but screening criteria poorly reflect health hazards, making it important to explore its biological pathways to develop effective prevention and treatment strategies.

Does exercise improve micro metabolic pathways and reduce health hazards in metabolically healthy obese individuals?

Design

Review

Authors

LSLiqiang SuJiangxi Normal UniversityYPYihe PanJiangxi Normal UniversityHCHaichun ChenFujian Normal University

Discussion

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Implication

May support exercise to reduce MHO risks; leaves open need for prospective trials confirming pathway effects.

Structured PICO

Does exercise improve micro metabolic pathways and reduce health hazards in metabolically healthy obese individuals?

P
Population
Metabolically healthy obese (MHO) individuals. The review included 99 articles.
I
Intervention
Exercise
O
Outcome
Improvement of micro metabolic pathways and reduction of MHO-related health hazards (cardiovascular disease and all-cause mortality risk)

Exercise is an important non-pharmacological strategy to correct underlying micro metabolic abnormalities and reduce long-term cardiovascular and metabolic disease risks in metabolically healthy obese individuals.

Limitations

  • The specific pathways, genes, proteins, and metabolites that play a key role and/or have high specificity in MHO micro metabolic disorder are not well understood.

Cite This Study

Su et al. (2022) conducted a review in Metabolically Healthy Obesity. Exercise was evaluated. Exercise can correct the abnormal micro metabolic pathways of metabolically healthy obesity, regulating metabolic homeostasis and reducing MHO-related health hazards.

synapsesocial.com/papers/6a15623479ff98d0de4e8c8ehttps://doi.org/10.3389/fphys.2022.924649
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adipokines Level in Metabolically Healthy Obese Saint-Petersburg Inhabitants (ESSE-RF)2016 · 12 citations
  2. 2New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk2016 · 320 citations
  3. 3Effects of a 12-week Exercise Training Programme on Aerobic Fitness, Body Composition, Blood Lipids and C-Reactive Protein in Adolescents with Obesity2008 · 190 citations