Key result
Right ventricular pacing in patients with Tetralogy of Fallot resulted in a 4% prevalence of pacemaker-induced cardiomyopathy and was not associated with a significant temporal decline in left ventricular ejection fraction.
Why the study?
Does frequent right ventricular pacing cause temporal decline in LVEF or pacing-induced cardiomyopathy in patients with Tetralogy of Fallot?
Cohort (n=58)
No
Does frequent right ventricular pacing cause temporal decline in LVEF or pacing-induced cardiomyopathy in patients with Tetralogy of Fallot?
Absolute Event Rate: -4% vs 3%
p-value: p=0.318
In patients with Tetralogy of Fallot, frequent right ventricular pacing is not significantly associated with a temporal decline in left ventricular systolic function, though pacing-induced cardiomyopathy occurs in a small minority.
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Egbe et al. (2019) conducted a cohort in Tetralogy of Fallot (n=58). Right ventricular pacing vs. Atrial pacing or biventricular pacing was evaluated on Temporal change in left ventricular ejection fraction (LVEF post-pre) at 2 years (p=0.318). Right ventricular pacing in patients with Tetralogy of Fallot resulted in a 4% prevalence of pacemaker-induced cardiomyopathy and was not associated with a significant temporal decline in left ventricular ejection fraction.
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