Key result
Among 1,221 patients undergoing pulmonary vein antrum isolation, 0 patients with paroxysmal atrial fibrillation and normal ejection fraction had left atrial appendage thrombus.
Why the study?
Does computed tomography adequately screen for left atrial appendage thrombus in patients with paroxysmal atrial fibrillation and normal ejection fraction presenting for pulmonary vein antrum isolation?
Cohort (n=1,221)
Does computed tomography adequately screen for left atrial appendage thrombus in patients with paroxysmal atrial fibrillation and normal ejection fraction presenting for pulmonary vein antrum isolation?
In patients with paroxysmal atrial fibrillation and normal ejection fraction undergoing PVAI, the incidence of LAA thrombus is zero, suggesting pre-procedural CT alone may be sufficient without routine TEE.
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May support CT-only LAA screening without routine TEE in paroxysmal AF with normal EF; leaves open prospective validation.
Khan et al. (2008) conducted a cohort in Paroxysmal atrial fibrillation (n=1,221). Computed tomography (CT) screening vs. Transesophageal echocardiography (TEE) was evaluated on Incidence of left atrial appendage (LAA) thrombus. Among 1,221 patients undergoing pulmonary vein antrum isolation, 0 patients with paroxysmal atrial fibrillation and normal ejection fraction had left atrial appendage thrombus.
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