Tumor infiltrating T lymphocytes expressing FoxP3, CCR7 or PD-1 predict the outcome of prostate cancer patients subjected to salvage radiotherapy after biochemical relapse

Valerio Nardone; Cirino Botta; Michele Caraglia; Elodia Claudia Martino; Maria Raffaella Ambrosio; Tommaso Carfagno; Paolo Tini; Leonardo Semeraro; Gabriella Misso; Anna Grimaldi; Mariarosaria Boccellino; Gaetano Facchini; Massimiliano Berretta; Gianluca Vischi; Bruno Jim Rocca; Aurora Barone; Pierfrancesco Tassone; Pierosandro Tagliaferri; Maria Teresa Del Vecchio; Luigi Pirtoli; Pierpaolo Correale

doi:10.1080/15384047.2016.1235666

Abstract

TIL scores correlated to a prolonged PFS and OS. These results suggest that the immunological microenvironment of primary tumor is strictly correlated with patient outcome and provide the rationale for immunological treatment of prostate cancer.

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Nardone et al. (2016) studied this question.

synapsesocial.com/papers/6a158f5f9b87f33fc69fa992 https://doi.org/10.1080/15384047.2016.1235666

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Tumor infiltrating T lymphocytes expressing FoxP3, CCR7 or PD-1 predict the outcome of prostate cancer patients subjected to salvage radiotherapy after biochemical relapse

Abstract

Discussion

Cite This Study

Tumor infiltrating T lymphocytes expressing FoxP3, CCR7 or PD-1 predict the outcome of prostate cancer patients subjected to salvage radiotherapy after biochemical relapse

Abstract

Discussion

Cite This Study

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