Key result
Bifurcation angle asymmetry in a left main coronary artery model plays a prominent role in determining pressure drop and recirculation area, with relatively unnoticeable effects on wall shear stress.
Why the study?
Does bifurcation angle asymmetry affect recirculation flow, pressure drop, and wall shear stress in a left main coronary artery model?
Does bifurcation angle asymmetry affect recirculation flow, pressure drop, and wall shear stress in a left main coronary artery model?
In a computational model of the left main coronary artery, bifurcation angle asymmetry significantly impacts pressure drop and recirculation area, but not wall shear stress.
Model findings on left main asymmetry do not warrant clinical changes; leaves open relevance to plaque progression pending validation.
This study was to investigate the effect of the bifurcation angle asymmetry on recirculation flow, pressure drop and wall shear stress (WSS) in an atherosclerotic model of a left coronary artery with left anterior descending (LAD) and left circumflex (LCX) branches. The linear regression analysis results showed that there is a positive correlation between WSS and bifurcation angle asymmetry. However, small increase in the WSS magnitude due to the increase in bifurcation angle asymmetry revealed the angle asymmetry does not seem to have a profound effect on the WSS. The results also showed that the bifurcation angle asymmetry play a prominent role in determining the pressure drop and recirculation area, while having relatively unnoticeable effects on the wall shear stress (WSS).
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Javadzadegan et al. (2014) studied Atherosclerotic left coronary artery model. Bifurcation angle asymmetry was evaluated on Recirculation flow, pressure drop and wall shear stress. Bifurcation angle asymmetry in a left main coronary artery model plays a prominent role in determining pressure drop and recirculation area, with relatively unnoticeable effects on wall shear stress.
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