Explaining variations in general practice prescribing costs per ASTRO-PU (age, sex, and temporary resident originated prescribing unit): Table 1

care make interpretation of mismatches difficult and require judgments based on the strength of the evi- dence in different settings, feasibility, and potential dangers.There is little evidence to support many guideline recommendations about what general prac- titioners should do, including routine examination, educational advice or advice on activities advice, and back exercises.General practitioners should probably be more aware of danger symptoms, advise patients with uncomplicated back pain to mobilise themselves early, and, with some reservations, consider arranging manipulation for persisting symptoms.Guidelines should be audited: standards should include accepted criteria,"5 discussion study methodology and the setting of evidence, and clear referencing of recom- mendations.More research based in general practice is needed to inform general practitioner assessment and management ofback pain.