Key result
This review evaluates the epidemiology, pathogenesis, non-invasive diagnostic techniques, and therapeutic interventions for hibernating myocardium in patients with ischemic cardiomyopathy.
This review summarizes the epidemiology, pathogenesis, non-invasive diagnostic techniques, and therapeutic interventions for hibernating myocardium in ischemic cardiomyopathy.
Provides a synthesis to inform evaluation of hibernating myocardium in ischemic cardiomyopathy; leaves open the need for randomized trials on revascularization.
Heart failure is placing an ever-increasing burden on society. Many subjects with heart failure and underlying coronary artery disease have a significant amount of akinetic but viable myocardium that is able to contract should myocardial perfusion improve (hibernating myocardium). Non-randomised studies have shown prognostic benefit in subjects with hibernating myocardium undergoing revascularisation. Several non-invasive techniques have been developed to assess the presence or absence of hibernating myocardium. This review will examine the epidemiology and underlying pathogenesis of hibernating myocardium; evaluate the non-invasive techniques for diagnosing hibernating myocardium, and look at therapeutic intervention in subjects with hibernating myocardium.
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Galasko et al. (2003) conducted a review in Ischaemic Cardiomyopathy with Hibernating Myocardium. Non-invasive assessment techniques was evaluated. This review evaluates the epidemiology, pathogenesis, non-invasive diagnostic techniques, and therapeutic interventions for hibernating myocardium in patients with ischemic cardiomyopathy.
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