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August 16, 2000Organic Letters

Regioselective Synthesis of 1,3,5-Triaryl-4-alkylpyrazoles: Novel Ligands for the Estrogen Receptor

Ying Huang John A. Katzenellenbogen

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Abstract

[reaction: see structure] A regioselective synthesis of 4-alkyl-1,3,5-triarylpyrazoles has been developed for the preparation of unsymmetrically substituted systems of interest as ligands for the estrogen receptor.

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Huang et al. (2000) studied this question.

synapsesocial.com/papers/6a15ed5bcaf7e3ea0ee3dea9 https://doi.org/10.1021/ol0062650

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