Key result
Accelerated 3D UTE-Cones imaging with compressed sensing proves feasible for human knee joint parameter mapping.
Why the study?
Quantitative ultrashort echo time (qUTE) imaging suffers from long acquisition time due to multiple acquisitions required for parameter estimation.
Compressed sensing reconstruction may enable accelerated quantitative 3D UTE-Cones imaging for evaluating human knee joint tissues.
Supports technical feasibility of accelerated knee UTE-Cones mapping; leaves open clinical validation before adoption.
Quantitative ultrashort echo time (qUTE) imaging suffers from long acquisition time due to multiple acquisitions required for parameter estimation. In this study, feasibility of accelerated qUTE Cones imaging with compressed sensing (CS) reconstruction is investigated for fast variable flip angle UTE-T 1 mapping, adiabatic UTE-T 1ρ mapping, and UTE quantitative magnetization transfer (MT) modelling of macromolecular fraction (MMF). We explored these biomarkers for qUTE-Cones imaging of in vivo human knee joints at various undersampling rates. The performance of CS-reconstruction and parameter mapping was evaluated in tendons, ligaments, menisci, and cartilage.
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Athertya et al. (2023) studied Human knee joints. Accelerated qUTE Cones imaging with compressed sensing (CS) reconstruction was evaluated on Performance of CS-reconstruction and parameter mapping in tendons, ligaments, menisci, and cartilage. Accelerated quantitative 3D UTE-Cones imaging with compressed sensing reconstruction is feasible for parameter mapping of in vivo human knee joints at various undersampling rates.
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