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March 1, 2018Organic Letters64 citations

Synthesis of Di(hetero)arylamines from Nitrosoarenes and Boronic Acids: A General, Mild, and Transition-Metal-Free Coupling

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SRSilvia RoscalesACAurelio G. Csákÿ

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Abstract

The synthesis of di(hetero)arylamines by a transition-metal-free cross-coupling between nitrosoarenes and boronic acids is reported. The procedure is experimentally simple, fast, mild, and scalable and has a wide functional group tolerance, including carbonyls, nitro, halogens, free OH and NH groups. It also permits the synthesis of sterically hindered compounds.

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Roscales et al. (2018) studied this question.

synapsesocial.com/papers/6a162036dca1af9bedbfa27ahttps://doi.org/10.1021/acs.orglett.8b00473
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