Key result
Monocusp reconstruction with a transannular patch prolonged the interval to grade 3-4 pulmonary regurgitation aggravation compared to patch alone (6.5 vs 3.8 years; p=0.037).
Why the study?
Does monocusp reconstruction with a transannular patch delay the aggravation of pulmonary regurgitation in patients undergoing tetralogy of Fallot repair?
Cohort (n=36)
Does monocusp reconstruction with a transannular patch delay the aggravation of pulmonary regurgitation in patients undergoing tetralogy of Fallot repair?
Absolute Event Rate: 64% vs 70%
p-value: p=0.735
Monocusp reconstruction with a transannular patch during tetralogy of Fallot repair significantly prolongs the interval to severe pulmonary regurgitation aggravation compared to patch alone.
May support monocusp use in tetralogy of Fallot repair to delay severe pulmonary regurgitation; hypothesis-generating and requires randomized confirmation.
BACKGROUND: Monocusp reconstruction with a transannular patch (TAP) results in early improvement because it relieves residual volume hypertension during the immediate postoperative period. However, few reports have assessed the long-term surgical outcomes of this procedure. The purpose of the present study was to evaluate the mid-term surgical outcomes of tetralogy of Fallot (TOF) repair using monocusp reconstruction with a TAP. METHODS: Between March 2000 and March 2009, 36 patients with a TOF received a TAP. A TAP with monocusp reconstruction (group I) was used in 25 patients and a TAP without monocusp reconstruction (group II) was used in 11 patients. We evaluated hemodynamic parameters using echocardiography during the follow-up period in both groups. RESULTS: At the most recent follow-up echocardiography (mean follow-up, 8.2 years), the mean pulmonary valve velocities of the patients in group I and group II were 2.1±1.0 m/sec and 0.9±0.9 m/sec, respectively (p=0.001). Although the incidence of grade 3-4 pulmonary regurgitation (PR) was not significantly different between the two groups (group I: 16 patients, 64.0%; group II: 7 patients, 70.0%; p=0.735) during the follow-up period, the interval between the treatment and the incidence of PR aggravation was longer in group I than in group II (group I: 6.5±3.4 years; group II: 3.8±2.2 years; p=0.037). CONCLUSION: Monocusp reconstruction with a TAP prolonged the interval between the initial treatment and grade 3-4 PR aggravation. Patients who received a TAP with monocusp reconstruction to repair TOF were not to progress to pulmonary stenosis during the follow-up period as those who received a TAP without monocusp reconstruction.
No takes yet. Share an insight, caveat, or question.
Jang et al. (2016) conducted a cohort in Tetralogy of Fallot (TOF) (n=36). Transannular patch (TAP) with monocusp reconstruction vs. Transannular patch (TAP) without monocusp reconstruction was evaluated on Incidence of grade 3-4 pulmonary regurgitation (PR) (p=0.735). Monocusp reconstruction with a transannular patch prolonged the interval to grade 3-4 pulmonary regurgitation aggravation compared to patch alone (6.5 vs 3.8 years; p=0.037).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: