Higher Body Mass Index Is Associated with Smaller Hamstring Autograft Diameter in Primary Anterior Cruciate Ligament Reconstruction: A Consecutive Cohort Study

BACKGROUND: Hamstring autograft diameter is an important determinant of mechanical strength and clinical outcomes after anterior cruciate ligament (ACL) reconstruction. Smaller graft diameters, particularly those below 8 mm, have been associated with increased risk of graft failure. While several anatomical and demographic factors influencing graft size have been investigated, the potential influence of systemic metabolic factors such as obesity and comorbidity burden on autograft morphology remains poorly understood. METHODS: ). Systemic comorbidity burden was quantified using the Charlson Comorbidity Index (CCI). The primary outcome was intraoperative hamstring graft diameter measured using a calibrated sizing block. The secondary outcome was graft diameter <8 mm. Multivariable linear regression was used to assess independent predictors of graft diameter, while logistic regression evaluated factors associated with grafts <8 mm. Models were adjusted for age, sex, and comorbidity burden. RESULTS: (difference -0.62 mm; p = 0.001). Higher BMI was statistically significant for increased odds of graft diameter <8 mm (adjusted OR 1.68; 95% CI, 1.18 to 2.39; p = 0.004). Comorbidity burden was not independently associated with graft diameter or with the probability of grafts <8 mm. CONCLUSION: Higher BMI is independently associated with smaller hamstring autograft diameter and with an increased likelihood of obtaining a graft measuring less than 8 mm during primary ACL reconstruction. These findings suggest that systemic anthropometric factors may influence intraoperative graft characteristics and should be considered during preoperative planning and graft selection strategies. LEVEL OF EVIDENCE: Level III, retrospective cohort study.