A Case of Rectal Cancer with Multiple Metachronous Intramural Metastases on the Oral Side

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Key Points

To report a rare case of metachronous intramural metastases in a patient with rectal cancer and examine its pathological features.
Performed laparoscopic high anterior resection with D3 lymphadenectomy and DST anastomosis.
Conducted postoperative cancer marker assessments and endoscopic evaluations.
Analyzed pathology from surgical specimens to confirm intramural metastasis.
Postoperative increase in tumor markers was observed after surgery.
Endoscopic examination revealed a 15mm submucosal tumor-like lesion at the anastomosis site.
Pathological analysis confirmed intramural metastases with specific histological characteristics.

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Case study reports metachronous intramural metastases in rectal cancer, highlighting its rarity and clinical implications.

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Yoshida et al. (2026) studied this question.

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