Neuropsychiatric problems in systemic lupus erythematosus.

Kaposi,L in his original description of systemic lupus erythema- tosus (S.L.E.), noted recurrent delirium in 2 out of 11 patients. During the past few years there has been a resurgence of interest in the central nervous system manifestations of S.L.E., together with an increasing awareness of their importance. In a recent large prospective study of S.L.E., central nervous system involvement, including psychosis, was seen in 59% of patients and was second only to renal involvement as a cause of death.'