Ultrasensitive Triple-Mode Nile Red-L64 Niosome Nanothermometers for Real-Time Cellular Thermogenesis Mapping

Ronak Lazarus; Rupal Kothari; Venkata Vamsi Krishna Venuganti; Amit Nag

doi:10.1039/d6an00434b

January 1, 2026The Analyst

Ultrasensitive Triple-Mode Nile Red-L64 Niosome Nanothermometers for Real-Time Cellular Thermogenesis Mapping

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Key Points

This research aims to develop ultrasensitive nanothermometers to accurately measure temperature changes in living cells, enhancing our understanding of cellular energy pathways.
Developed triple-mode niosome nanothermometers using Nile Red-L64 for ultra-sensitive temperature measurements.
Performed real-time temperature mapping in live cells to assess intracellular thermogenesis.
Analyzed temperature fluctuations with precision ranging from 0.1°C to 0.2°C.
Successfully measured minimal temperature changes in live cells, achieving an accuracy of ±0.1°C.
Revealed significant variations in temperature dynamics linked to metabolic activity, demonstrating the capability of the nanothermometers.
Establishing a new standard for real-time monitoring of cellular thermogenesis without invasive procedures.

Implication

Demonstrates real-time mapping of cellular thermogenesis using niosome nanothermometers, indicating new insights into metabolic pathways.

Abstract

Temperature dynamics in living cells provide critical insights into metabolic processes and cellular energy pathways. However, precise intracellular thermometry to measure minimal temperature fluctuations, typically 0.1°C -0.2°C change in the...

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Cite This Study

Lazarus et al. (2026) studied this question.

synapsesocial.com/papers/6a1689eb0c924ddd1bd58856 https://doi.org/10.1039/d6an00434b

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Ultrasensitive Triple-Mode Nile Red-L64 Niosome Nanothermometers for Real-Time Cellular Thermogenesis Mapping

Key Points

Implication

Abstract

Discussion

Cite This Study

Ultrasensitive Triple-Mode Nile Red-L64 Niosome Nanothermometers for Real-Time Cellular Thermogenesis Mapping

Key Points

Implication

Abstract

Discussion

Cite This Study

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