Case report reveals clinical and biochemical variability in composite pheochromocytomas, highlighting the need for high suspicion in diagnosis.
Composite pheochromocytomas are a rare subset of pheochromocytomas composed of chromaffin cell tumors and neurogenic tumors. Their clinical manifestations may be atypical for pheochromocytoma. Here, we present 3 cases that illustrate the broad spectrum of disease seen in composite pheochromocytomas. A high level of clinical suspicion is needed to diagnose composite pheochromocytomas given their rarity and diverse clinical presentations.
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Lee et al. (2026) studied this question.
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