Why the study?
Long-term corticosteroid therapy for oral lichen planus can cause adverse effects and may be ineffective for some patients, prompting evaluation of photodynamic therapy as an alternative.
Does photodynamic therapy improve outcomes compared to corticosteroid therapy in patients with oral lichen planus?
Meta-Analysis (n=587)
Yes
Does photodynamic therapy improve outcomes compared to corticosteroid therapy in patients with oral lichen planus?
Answers are grounded in this paper and cite their sources.
Photodynamic therapy demonstrates comparable efficacy to corticosteroid therapy for oral lichen planus, offering a viable non-steroidal alternative.
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Naruse et al. (2026) conducted a meta-analysis in Oral lichen planus (n=587). Photodynamic therapy (PDT) vs. Corticosteroid therapy (CST) was evaluated on Total effective rate for OLP treatment, improvement in Visual Analogue Scale (VAS) score, Thongprasom (TH) sign score, or lesion area (p=>0.05).
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