Key result
Black patients face ~24% lower odds of receiving thrombolysis than White patients despite Target: Stroke.
Why the study?
It was unknown whether the nationwide Target: Stroke quality initiative improved stroke thrombolysis care metrics and clinical outcomes across racial and ethnic groups.
Does the Target: Stroke quality initiative improve thrombolysis rates and time metrics across different racial and ethnic groups in patients with acute ischemic stroke?
Cohort (n=1,189,234)
Yes
Does the Target: Stroke quality initiative improve thrombolysis rates and time metrics across different racial and ethnic groups in patients with acute ischemic stroke?
Effect estimate: aOR 0.76 (95% CI 0.74-0.78)
While a nationwide quality initiative improved stroke thrombolysis rates and times overall, significant racial and ethnic disparities persist, with Asian, Black, and Hispanic patients less likely to receive timely treatment compared to White patients.
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Persistent disparities in thrombolysis persist after Target: Stroke; leaves open whether equity-focused modifications can reduce racial gaps.
Man et al. (2024) conducted a cohort in Acute ischemic stroke (n=1,189,234). Target: Stroke (TS) quality initiative vs. Pre-TS period and White patients was evaluated on Thrombolysis rates and time metrics (aOR 0.76, 95% CI 0.74-0.78). The Target: Stroke initiative improved thrombolysis rates, but Black patients had significantly lower odds of receiving thrombolysis than White patients in phase III (aOR 0.76; 95% CI 0.74-0.78).
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