What does this research mean for the field?

Following a myocardial infarction, the remaining noninfarcted viable myocardium experiences a distinct, reversible decline in contractility during the early phase that normalizes within six weeks. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 1, 1976Circulation ResearchOpen Access

Experimental myocardial infarction in the cat. I. Reversible decline in contractility of noninfarcted muscle.

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Why the study?

Does experimental myocardial infarction cause a decline in contractility of the noninfarcted myocardium in adult cats?

Structured PICO

Does experimental myocardial infarction cause a decline in contractility of the noninfarcted myocardium in adult cats?

Population

Adult cats

Intervention

Experimental myocardial infarction produced by ligation of several branches of the left coronary artery

Outcome

Contractile state of the noninfarcted myocardium (actively developed force at Lmax and rate of force development)surrogate

Experimental myocardial infarction in cats causes a distinct but reversible loss of contractility in the remaining viable noninfarcted myocardium during the early post-infarction phase.

Discussion

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Implication

Transient remote contractile impairment may occur early post-MI; leaves open translation to human remodeling and recovery.

Cite This Study

Mathes et al. (1976) studied this question.

synapsesocial.com/papers/6a16ac65798df06fa4b268de https://doi.org/10.1161/01.res.38.6.540

View Full Paper

Ask AI

Bookmark

Experimental myocardial infarction in the cat. I. Reversible decline in contractility of noninfarcted muscle.

Structured PICO

Discussion

Implication

Cite This Study

Experimental myocardial infarction in the cat. I. Reversible decline in contractility of noninfarcted muscle.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider