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July 12, 2020Contact Dermatitis11 citationsOpen Access

First case of DRESS syndrome caused by hydroxychloroquine with a positive patch test

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ACAraceli Castro-JiménezInstituto de Investigación Biosanitaria de GranadaNNNuria Navarrete NavarreteInstituto de Investigación Biosanitaria de GranadaAGAlejandro Raúl Gratacós GómezServicio de Salud de Castilla La Mancha

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Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, (formerly known as drug-induced hypersensitivity syndrome) is an acute, idiosyncratic, and potentially life-threatening drug reaction, characterized by fever (>38.5 C), skin eruptions, and haematological abnormalities. The most frequently involved drugs are anticonvulsants, sulfonamides, allopurinol, and antibiotics, while hydroxychloroquine has been rarely reported as causative agent.

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Castro-Jiménez et al. (2020) studied this question.

synapsesocial.com/papers/6a16f1052fcf950e0005764chttps://doi.org/10.1111/cod.13657
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hydroxychloroquine-induced DRESS syndrome2007 · 44 citations
  2. 2Multiple Drug Hypersensitivity Syndrome to Antituberculosis Drugs: A Case Report2019 · 8 citations
  3. 3Spanish Guidelines for Diagnosis, Management, Treatment, and Prevention of DRESS Syndrome2020 · 147 citations
  4. 4Drug reaction with eosinophilia and systemic symptoms syndrome to hydroxychloroquine, an old drug in the spotlight in the COVID‐19 era2020 · 29 citations
  5. 5Pulmonary Manifestations of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: A Systematic Review2019 · 108 citations