Why the study?
Is coronary venous endothelin concentration elevated in patients with unstable angina compared to stable angina?
Population
12 patients with angina undergoing cardiac catheterisation and coronary arteriography, along with healthy…
Design
Cross-sectional
Key result
Coronary venous endothelin concentrations were not significantly different between patients with unstable angina (2.32 ng/l) and stable angina (2.77 ng/l).
Authors
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Endothelin unlikely to modulate coronary tone in unstable angina; cross-sectional data leaves open its relevance in broader ACS populations.
Observational (n=12)
Is coronary venous endothelin concentration elevated in patients with unstable angina compared to stable angina?
Coronary venous endothelin concentrations are not significantly elevated in unstable angina compared to stable angina or healthy controls, suggesting it does not modulate coronary arterial tone in this setting.
Absolute Event Rate: 2.32% vs 2.77%
Stewart et al. (1991) conducted an observational in Stable or unstable angina (n=12). Unstable angina vs. Stable angina was evaluated on Coronary venous endothelin concentration. Coronary venous endothelin concentrations were not significantly different between patients with unstable angina (2.32 ng/l) and stable angina (2.77 ng/l).