Allotypic specificities were identified on two different myeloma proteins and the corresponding normal gammaG-immunoglobulins of BALB/c mice. When the sera of F(2) progeny from a cross between BALB/c mice having the a1 allotype and AL mice having the a4 allotype were tested for these specificities, it was found that the two allotypic specificities of the BALB/c mice were either both present (87 mice) or both absent (36 mice), an indication of linkage in their genetic control.
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Lieberman et al. (1965) studied this question.
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