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August 29, 2018SLEEPOpen Access

Posttraumatic stress disorder diagnosis is associated with reduced parasympathetic activity during sleep in US veterans and military service members of the Iraq and Afghanistan wars

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Why the study?

Does PTSD diagnosis reduce high-frequency heart rate variability during sleep in US veterans?

Population

62 post-9/11 US military veterans and service members (29 with PTSD, 33 without PTSD)

Comparison

Posttraumatic stress disorder (PTSD) diagnosis vs No PTSD diagnosis

Design

Cross-sectional

Key result

US veterans and service members with PTSD had significantly lower high-frequency heart rate variability during overall NREM sleep compared to those without PTSD (p = .04).

Authors

CUChristi S. UlmerMHMartica H. HallPDPaul A. Dennis

Discussion

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Overview

PTSD linked to blunted parasympathetic tone during NREM sleep in veterans; hypothesis-generating for autonomic CVD pathways, needs prospective confirmation.

Study Design

Type

Observational (n=62)

Structured PICO

Does PTSD diagnosis reduce high-frequency heart rate variability during sleep in US veterans?

P
Population
62 post-9/11 US military veterans and service members (29 with PTSD, 33 without PTSD)
I
Intervention
Posttraumatic stress disorder (PTSD) diagnosis
C
Comparator
No PTSD diagnosis
O
Outcome
High-frequency heart rate variability (HF-HRV) during NREM and REM sleepsurrogate

Main Result

p-value: p=.04

PTSD is associated with blunted parasympathetic modulation during NREM sleep in young veterans, potentially contributing to increased cardiovascular disease risk.

Cite This Study

Ulmer et al. (2018) conducted an observational in Posttraumatic stress disorder (PTSD) (n=62). PTSD diagnosis vs. Without PTSD was evaluated on High-frequency heart rate variability (HF-HRV) during overall NREM sleep (p=.04). US veterans and service members with PTSD had significantly lower high-frequency heart rate variability during overall NREM sleep compared to those without PTSD (p = .04).

synapsesocial.com/papers/6a17054bb13aec50ea6bc4b8https://doi.org/10.1093/sleep/zsy174
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