Key result
Transcatheter atrial septal defect occlusion in 3 pregnant patients with Ebstein's anomaly resulted in favorable maternal and fetal outcomes, with significant symptom reduction and cyanosis resolution.
Why the study?
Does transcatheter atrial septal defect occlusion improve symptoms and resolve cyanosis in pregnant women with Ebstein's anomaly?
Case Report (n=3)
Does transcatheter atrial septal defect occlusion improve symptoms and resolve cyanosis in pregnant women with Ebstein's anomaly?
Transcatheter atrial septal defect occlusion can be safely and effectively performed during pregnancy in women with Ebstein's anomaly and cyanosis, provided careful hemodynamic testing confirms right ventricular capacity.
May support transcatheter ASD closure for symptom relief in select pregnant Ebstein cases; leaves open need for larger prospective studies.
Transcatheter atrial septal defect occlusion is described in three pregnant patients with Ebstein's anomaly and exercise-induced cyanosis. Procedures took place in the second and third trimester. Careful hemodynamic testing was performed prior to permanent atrial septal occlusion to confirm the capacity of the right ventricle to accept the entirety of systemic venous return in the volume-expanded state of pregnancy. Outcomes for mother and fetus were favorable in all patients with significant reduction in maternal symptoms and resolution of cyanosis.
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Houser et al. (2014) conducted a case report in Ebstein's anomaly with exercise-induced cyanosis during pregnancy (n=3). Transcatheter atrial septal defect occlusion was evaluated on Maternal and fetal outcomes, symptom reduction, and resolution of cyanosis. Transcatheter atrial septal defect occlusion in 3 pregnant patients with Ebstein's anomaly resulted in favorable maternal and fetal outcomes, with significant symptom reduction and cyanosis resolution.
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