Key result
Prior beta-blocker use shows no link to in-hospital AF development in STEMI patients.
Why the study?
Conflicting results exist regarding early beta-blocker administration on in-hospital mortality and arrhythmias, prompting investigation into the effects of chronic beta-blocker use on in-hospital AF development in STEMI patients.
Does chronic beta-blocker use prevent in-hospital atrial fibrillation development in patients with STEMI?
Cohort (n=814)
Does chronic beta-blocker use prevent in-hospital atrial fibrillation development in patients with STEMI?
Chronic beta-blocker use prior to admission does not significantly affect the development of in-hospital atrial fibrillation in patients presenting with STEMI.
Chronic beta-blocker use was not associated with lower in-hospital AF in STEMI; leaves open whether pre-admission therapy modifies arrhythmia risk.
BACKGROUND AND AIM: There are conflicting results about the early administration of beta-blockers (bb) on in-hospital mortality and arrhythmias. Here, we wanted to investigate the effects of chronic bb use on in-hospital Atrial Fibrillation (AF) development in ST-Elevation Myocardial Infarction (STEMI) patients. MATERIALS AND METHODS: A total of 814 consecutive patients with STEMI were included in the study. They were divided into two groups according to whether they are using bb on admission or not. They were followed for AF development in-hospital and predictors of AF were determined by multivariable logistic regression analysis. RESULTS: Of the 814 patients, 103 (12.67%) patients were already using bb, while 711 (87.3%) were not. There were no significant differences in the frequency of AF development [3 (%2.9) vs 30 (%4.2), p = .788] between the groups. Multivariable logistic regression analysis showed that left atrial (LA) diameter is the only independent predictor of in-hospital AF development. CONCLUSIONS: Our study showed that chronic bb use does not have an effect on in-hospital AF development in STEMI patients. Nevertheless, LA diameter was found to be an independent predictor of AF.
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Kahraman et al. (2022) conducted a cohort in ST-Elevation Myocardial Infarction (STEMI) (n=814). Chronic beta-blocker use vs. No chronic beta-blocker use was evaluated on In-hospital Atrial Fibrillation (AF) development (p=0.788). Chronic beta-blocker use prior to admission did not significantly affect the frequency of in-hospital atrial fibrillation development in STEMI patients (2.9% vs 4.2%; p=0.788).
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