Key result
Mitral annular plane systolic excursion on exercise effectively differentiated HFpEF patients from controls (AUC 0.901; 95% CI 0.835-0.967).
Why the study?
Does Mitral annular plane systolic excursion (MAPSE) on exercise accurately differentiate patients with HFpEF from healthy controls?
Case-Control (n=98)
Does Mitral annular plane systolic excursion (MAPSE) on exercise accurately differentiate patients with HFpEF from healthy controls?
Effect estimate: AUC 0.901 (95% CI 0.835-0.967)
Absolute Event Rate: 12% vs 16.2%
p-value: p=< 0.001
MAPSE measured during exercise is a simple and highly accurate echocardiographic tool for diagnosing HFpEF.
No takes yet. Share an insight, caveat, or question.
May support exercise MAPSE for HFpEF differentiation; hypothesis-generating and requires prospective validation.
Wenzelburger et al. (2011) conducted a case-control in Heart failure with preserved ejection fraction (HFpEF) (n=98). Mitral annular plane systolic excursion (MAPSE) on exercise vs. Control subjects was evaluated on MAPSE on exercise to differentiate between patients and controls (AUC 0.901, 95% CI 0.835-0.967, p=< 0.001). Mitral annular plane systolic excursion on exercise effectively differentiated HFpEF patients from controls (AUC 0.901; 95% CI 0.835-0.967).
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