First Enantioselective Synthesis of (R)‐Convolutamydine B and E with N‐(Heteroarenesulfonyl)prolinamides

Crossed-aldol reaction: The synthesis of (R)-convolutamydine E has been achieved by the crossed-aldol reaction of acetaldehyde with 4,6-dibromoisatin (1: X = Y = Br) by using a bifunctional organocatalyst. This strategy allows the enantioselective synthesis of (R)-convolutamydine E derivatives and convolutamydine B. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.