Poor mental health over time independently decreased mean survival time from all-cause mortality by 5.8% and hastened time to first cardiac hospitalization by 7.6% in prevalent hemodialysis patients.
Cohort (n=1,798)
Yes
Is poor mental health over time associated with increased all-cause mortality and cardiac outcomes in hemodialysis patients?
Poor mental health over time is independently associated with increased risks of all-cause mortality and cardiac events in hemodialysis patients, highlighting the need for mental health attention in this population.
Effect estimate: Mean Survival Estimate -0.06 (95% CI -0.10, -0.03)
p-value: p=<0.001
Summary Background and objectives Poor mental health over time is significantly associated with cardiovascular morbidity and mortality in the general population, which is the leading cause of death in dialysis patients. Most studies of dialysis patients, however, have investigated the relationship between baseline mental health measurements and all-cause mortality and not mental health measured longitudinally throughout a study and cause-specific mortality. Design, setting, participants, P <0.001), and they also significantly hastened time to first cardiac hospitalization by −0.08 (−0.13, −0.02; P =0.01) and composite of first cardiac hospitalization or cardiac death by −0.04 (−0.07, −0.02; P <0.001). Conclusions This study found an independent association between poor mental health over time and all-cause mortality, cardiac hospitalization, and the composite of cardiac death or cardiac hospitalization in hemodialysis patients. The results underscore the importance of attention to mental health related to cardiac complications and even death in dialysis patients.
Kang et al. (Fri,) conducted a cohort in End-stage renal disease on hemodialysis (n=1,798). Poor mental health over time (MHI score ≤60) vs. Better mental health (MHI score >60) was evaluated on All-cause mortality (Mean Survival Estimate -0.06, 95% CI -0.10, -0.03, p=<0.001). Poor mental health over time independently decreased mean survival time from all-cause mortality by 5.8% and hastened time to first cardiac hospitalization by 7.6% in prevalent hemodialysis patients.