To elucidate the ferredoxin-dependent redox system of the thermoacidophilic, aerobic archaeon Sulfolobus sp. strain 7, a novel FeS flavoprotein, which can reoxidize the reduced 7Fe ferredoxin in vitro, has been purified the 7Fe ferredoxin a of the of of FeS of reduced the reduced ferredoxin the ferredoxin-dependent redox system of Sulfolobus sp. strain ferredoxin To elucidate the ferredoxin-dependent redox system of the thermoacidophilic, aerobic archaeon Sulfolobus sp. strain 7, a novel FeS flavoprotein, which can reoxidize the reduced 7Fe ferredoxin in vitro, has been purified the 7Fe ferredoxin a of the of of FeS of reduced the reduced ferredoxin the ferredoxin-dependent redox system of Sulfolobus sp. strain ferredoxin the of in ferredoxin of a of in the in in ferredoxin a a the of a archaeon the the the ferredoxin-dependent redox system of aerobic Sulfolobus in the of aerobic aerobic in a aerobic which the of the of of aerobic in the of a of in the of a the in of reduced ferredoxin the of reduced ferredoxin in aerobic sp. strain Sulfolobus strain been Sulfolobus strain 7, sp. strain in of strain strain the a novel the been Sulfolobus strain 7, sp. strain in of strain strain the a novel the a aerobic archaeon archaeon aerobic a the the a of a 7Fe which has been in in of which the reduced the of the of in Sulfolobus been purified Sulfolobus sp. strain the in of the Sulfolobus the the in in elucidate reduced ferredoxin in Sulfolobus sp. strain 7, purified the the a archaeon the in system the Sulfolobus 7Fe in the of ferredoxin-dependent of ferredoxin-dependent the of the of of ferredoxin-dependent the of the of of of a novel FeS flavoprotein, of Sulfolobus sp. strain of Sulfolobus sp. strain Sulfolobus sp. strain in in the of the Sulfolobus ferredoxin which has been reduced the purified the system in of of the the purified Sulfolobus ferredoxin the in of the purified of the Sulfolobus the of in of a 7Fe a Sulfolobus sp. sp. strain in the of in a the of a the Sulfolobus 7Fe ferredoxin purified ferredoxin a a of of purified of the purified the of of the the purified purified in the of of a Sulfolobus the a which been of the the the a of in the of a been of the a in the the of the the the the of the of a which been of the the a of a in which been of a FeS a which purified a a a a in which a a a in of the redox of the purified FeS in a of in the of of redox redox a a of a a To the of of the the of a of the of the redox the a the of of the purified a a a which been the a of the purified a of purified in the of the of a the of of in the of in the of a the of the system in the of of of purified a of in the of the been of a of of the a of purified Sulfolobus sp. strain the of the 7Fe ferredoxin the of the the the purified reoxidize the reduced of the 7Fe ferredoxin in the of the Sulfolobus reoxidize ferredoxin been reduced in the of reoxidize the reduced 7Fe ferredoxin in the the of ferredoxin-dependent redox in FeS FeS of the Sulfolobus a reoxidize reduced a FeS the a which purified a in the of of the of of a of of the of the of the of Sulfolobus sp. strain a of in the of in purified the which of of of of of the of the of the of in the a of the the of the the of the Sulfolobus the of purified of FeS a in the the of which has been of of purified in the of the which the the of Sulfolobus sp. strain of the of the the the the the the of in of purified of Sulfolobus sp. strain in of the of the reduced in a the of the has a reduced has a in the a of the of purified of Sulfolobus sp. strain in the of a which of in the of of the can a reduced in the of a in the the of of of Sulfolobus sp. strain in the in the the of of in of the redox of the in a the of the redox of the the the the the the the FeS which has been the redox of the the a redox the of of of of the of the Sulfolobus in of redox redox a of of the of of purified reoxidize the reduced of the ferredoxin the of the of of purified ferredoxin ferredoxin the in the in the 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can reduced in the ferredoxin-dependent of which the Sulfolobus ferredoxin in the reduced of the redox of the the of the redox of the Sulfolobus ferredoxin which in of of in in a in a of of a of the 7Fe ferredoxin in the in system the the of a of of the redox of the Sulfolobus ferredoxin the the of of the in the the of a of the of the purified a of the ferredoxin-dependent redox system of Sulfolobus sp. strain ferredoxin a a redox a of the ferredoxin-dependent of the the of of a of the of Sulfolobus sp. strain ferredoxin-dependent of purified of of of in ferredoxin the of has been a has been aerobic which the of has been the ferredoxin-dependent redox system of the Sulfolobus ferredoxin the redox in the redox the of the which has a the a of the in Sulfolobus sp. strain the the aerobic the of the ferredoxin-dependent system in a ferredoxin the of in the of Sulfolobus sp. strain in the of elucidate the of the ferredoxin-dependent redox the of in ferredoxin of a of in the in in ferredoxin a a the of a archaeon the the the ferredoxin-dependent redox system of aerobic Sulfolobus in the of aerobic aerobic in a aerobic which the of the of of aerobic in the of a of in the of a the in of reduced ferredoxin the of reduced ferredoxin in aerobic Sulfolobus sp. strain Sulfolobus strain been Sulfolobus strain 7, sp. strain in of strain strain the a novel the been Sulfolobus strain 7, sp. strain in of strain strain the a novel the a aerobic archaeon archaeon aerobic a the the a of a 7Fe which has been in in of which the reduced the of the of in Sulfolobus been purified Sulfolobus sp. strain the in of the Sulfolobus the the in in To elucidate reduced ferredoxin in Sulfolobus sp. strain 7, purified the the a archaeon the in system the Sulfolobus 7Fe in the of ferredoxin-dependent of ferredoxin-dependent the of the of of ferredoxin-dependent the of the of of of a novel FeS flavoprotein, of Sulfolobus sp. strain of Sulfolobus sp. strain Sulfolobus sp. strain in in the of the Sulfolobus ferredoxin which has been reduced the reduced of Sulfolobus sp. strain reduced of Sulfolobus sp. strain purified the system in of of the the purified Sulfolobus ferredoxin the in of the purified of the Sulfolobus the of in of a 7Fe a Sulfolobus sp. sp. strain in the of in a the of a the Sulfolobus 7Fe ferredoxin purified ferredoxin a a of of purified of the purified the of of the the purified purified in the of of a Sulfolobus the a which been of the the the a of in the of a been of the a in the the of the the the the of the of a which been of the the a of a in which been of a FeS a which purified a a a a in which a a a in of the redox of the purified FeS in a of in the of of redox redox a a of a a To the of of the the of a of the of the redox the a the of of the purified a a a which been the a of the purified a of purified in the of the of a the of of in the of in the of a the of the system in the of of of purified a of in the of the been purified the system in of of the the purified 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of the the the of a of the of in the the in of the of the of redox of the in the the a of the Sulfolobus 7Fe ferredoxin ferredoxin the redox of the of the Sulfolobus 7Fe ferredoxin of the purified reduced the reduced Sulfolobus a of the ferredoxin in of purified reoxidize the reduced of the ferredoxin the of the of of purified ferredoxin ferredoxin the in the in the the of the of the can in the of of in the ferredoxin-dependent of of in the of the Sulfolobus ferredoxin of ferredoxin of the of the ferredoxin-dependent of the of the in of the the the of the of the the of a of the has a of the of in the the the a in a the the a of the the of of the of the the the of a of the of in the the in of the of the of redox of the in the the a of the Sulfolobus 7Fe ferredoxin ferredoxin the redox of the of the Sulfolobus 7Fe ferredoxin of the purified reduced the reduced Sulfolobus a of the ferredoxin in of a of the of reduced ferredoxin in aerobic of a novel FeS flavoprotein, in the ferredoxin-dependent redox system of the Sulfolobus sp. strain of in in the of reduced ferredoxin in Sulfolobus sp. strain the of can reduced in the ferredoxin-dependent of which the Sulfolobus ferredoxin in the reduced of the redox of the the of the redox of the Sulfolobus ferredoxin which in of of in in a in a of of a of the 7Fe ferredoxin in the in system the the of a of of the redox of the Sulfolobus ferredoxin the the of of the in the the of a of the of the purified a of the ferredoxin-dependent redox system of Sulfolobus sp. strain ferredoxin a a redox a of the ferredoxin-dependent of the the of of a of the of Sulfolobus sp. strain ferredoxin-dependent of purified of of of in ferredoxin the of has been a has been aerobic which the of has been the ferredoxin-dependent redox system of the Sulfolobus ferredoxin the redox in the redox the of the which has a the a of the in Sulfolobus sp. strain the the aerobic the of the ferredoxin-dependent system in a ferredoxin the of in the of Sulfolobus sp. strain in the of elucidate the of the ferredoxin-dependent redox of a of the of reduced ferredoxin in aerobic of a novel FeS flavoprotein, in the ferredoxin-dependent redox system of the Sulfolobus sp. strain of in in the of reduced ferredoxin in Sulfolobus sp. strain the of can reduced in the ferredoxin-dependent of which the Sulfolobus ferredoxin in the reduced of the redox of the the of the redox of the Sulfolobus ferredoxin which in of of in in a in a of of a of the 7Fe ferredoxin in the in system the the of a of of the redox of the Sulfolobus ferredoxin the the of of the in the the of a of the of the purified a of the ferredoxin-dependent redox system of Sulfolobus sp. strain ferredoxin a a redox a of the ferredoxin-dependent of the the of of a of the of Sulfolobus sp. strain ferredoxin-dependent of purified of of of in ferredoxin the of has been a has been aerobic which the of has been the ferredoxin-dependent redox system of the Sulfolobus ferredoxin the redox in the redox the of the which has a the a of the in Sulfolobus sp. strain the the aerobic the of the ferredoxin-dependent system in a ferredoxin the of in the of Sulfolobus sp. strain in the of elucidate the of the ferredoxin-dependent redox of a of the of reduced ferredoxin in aerobic of a novel FeS flavoprotein, in the ferredoxin-dependent redox system of the Sulfolobus sp. strain of in in the of reduced ferredoxin in Sulfolobus sp. strain the of can reduced in the ferredoxin-dependent of which the Sulfolobus ferredoxin in the reduced of the redox of the the of the redox of the Sulfolobus ferredoxin which in of of in in a in a of of a of the 7Fe ferredoxin in the in system the the of a of of the redox of the Sulfolobus ferredoxin the the of of the in the the of a of the of the purified a of the ferredoxin-dependent redox system of Sulfolobus sp. strain ferredoxin a a redox a of the ferredoxin-dependent of the the of of a of the of Sulfolobus sp. strain ferredoxin-dependent of purified of of of in ferredoxin the of reduced ferredoxin in aerobic of a novel FeS flavoprotein, in the ferredoxin-dependent redox system of the Sulfolobus sp. strain of in in the of reduced ferredoxin in Sulfolobus sp. strain the of can reduced in the ferredoxin-dependent of which the Sulfolobus ferredoxin in the reduced of the redox of the the of the redox of the Sulfolobus ferredoxin which in of of in in a in a of of a of the 7Fe ferredoxin in the in system the the of a of of the redox of the Sulfolobus ferredoxin the the of of the in the the of a of the of the purified a of the ferredoxin-dependent redox system of Sulfolobus sp. strain ferredoxin a a redox a of the ferredoxin-dependent of the the of of a of the of Sulfolobus sp. strain ferredoxin-dependent of purified of of of in ferredoxin the of has been a has been aerobic which the of has been the ferredoxin-dependent redox system of the Sulfolobus ferredoxin the redox in the redox the of the which has a the a of the in Sulfolobus sp. strain the the aerobic the of the ferredoxin-dependent system in a ferredoxin the of in the of Sulfolobus sp. strain in the of elucidate the of the ferredoxin-dependent redox has been a has been aerobic which the of has been the ferredoxin-dependent redox system of the Sulfolobus ferredoxin the redox in the redox the of the which has a the a of the in Sulfolobus sp. strain the the aerobic the of the ferredoxin-dependent system in a ferredoxin the of in the of Sulfolobus sp. strain in the of elucidate the of the ferredoxin-dependent redox the in the redox of of the of the of
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Iwasaki et al. (1995) studied this question.
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