Key result
Catheter ablation for spontaneous scar-based atrial flutter achieved acute success in 85.7% of right AFL and 100% of left AFL patients (P=0.304), with higher recurrence in right AFL.
Why the study?
What are the electrophysiologic characteristics and ablation outcomes of spontaneous scar-based right versus left atrial flutter?
Cohort (n=12)
What are the electrophysiologic characteristics and ablation outcomes of spontaneous scar-based right versus left atrial flutter?
Absolute Event Rate: 85.7% vs 100%
p-value: p=0.304
Spontaneous scar-based right atrial flutter is associated with larger scar areas, higher recurrence rates, and greater need for pacemaker implantation compared to left atrial flutter.
May warrant closer post-ablation surveillance for right AFL; leaves open optimal strategies for scar-based flutter subtypes.
BACKGROUND: The understanding of spontaneous scar-based reentrant atrial arrhythmia is limited. We aim to characterize the electrophysiologic and mapping features of spontaneous scar-based atrial flutter (AFL) and outcomes of catheter ablation. METHODS: Consecutive patients with a diagnosis of AFL who underwent catheter ablation from January 2012 to June 2015 were screened. Scars were detected in 12 patients and were included in this study. All had negative coronary angiography. These patients were divided into right AFL (seven patients) and left AFL groups (five patients) based on electrophysiologic mappings. RESULTS: Compared to patients with right AFL, the size of right atrium (RA) was smaller and left atrium (LA) was larger in the left AFL group. The proportion of the scar area was 11.1 ± 11.7 % in the RA AFL group and 7.8 ± 2.8 % in the LA AFL group. The difference was significant (P = 0.001). The acute success rates of ablation were 85.7% and 100%, respectively, in patients with right and left AFL (P = 0.304). During the follow-up, expansion of the scar area was noted in three patients with recurrent right AFL. No scar expansion was noted in one patient with recurrent left AFL. In addition, three patients with right AFL required permanent pacemaker implantation for sinus node dysfunction, and no one required pacemaker in patients with left AFL. CONCLUSIONS: Spontaneous scar could serve as substrate for AFL in RA or LA. Compared to left AFL, there was a higher rate of recurrence and pacemaker implantation in patients with right AFL.
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Lei et al. (2018) conducted a cohort in Spontaneous scar-based reentrant atrial flutter (n=12). Catheter ablation for right atrial flutter vs. Catheter ablation for left atrial flutter was evaluated on Acute success rate of ablation (p=0.304). Catheter ablation for spontaneous scar-based atrial flutter achieved acute success in 85.7% of right AFL and 100% of left AFL patients (P=0.304), with higher recurrence in right AFL.
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