Why the study?
Does the relationship between mean arterial pressure and muscle cellular pH during ischaemia after sustained handgrip follow a linear pattern or exhibit a threshold?
Does the relationship between mean arterial pressure and muscle cellular pH during ischaemia after sustained handgrip follow a linear pattern or exhibit a threshold?
The muscle chemoreflex exhibits a clear threshold around a muscle pH of 6.90 units, below which mean arterial pressure increases linearly in response to further decreases in pH.
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Nonlinear MAP-pH response during ischemia suggests threshold effects; leaves open clinical translation.
Nishiyasu et al. (1994) studied this question.
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