Key result
The EClysis software demonstrated a high level of agreement with the CSE database reference values for the detection of PQRST points, with regression coefficients above 0.95 (P < 0.0001).
Why the study?
Does EClysis software accurately measure PQRST wave onsets and offsets compared to reference standards in normal and pathological ECGs?
Observational (n=125)
No
Does EClysis software accurately measure PQRST wave onsets and offsets compared to reference standards in normal and pathological ECGs?
Effect estimate: r > 0.98
p-value: p=<0.0001
The EClysis software provides highly accurate automated measurements of ECG PQRST intervals comparable to expert cardiologists and reference computer programs.
May support automated ECG analysis in practice; leaves open prospective outcome studies.
BACKGROUND: PC-based ECG measurements must cope with normal as well as pathological ECGs in a reliable manner. EClysis, a software for ECG measurements was tested against reference values from the Common Standards for Quantitative Electrocardiography (CSE) database. METHODS: Digital ECGs (12 leads, 500 Hz) were recorded by the CSE project. Data Set 3 contains reference values for 125 ECGs (33 normal and 92 pathological). Median values of measurements by 11 computer programs and by five cardiologists, respectively, refer to the earliest P and QRS onsets and to the latest P, QRS, and T offsets in any lead of a selected (index) beat. EClysis automatically measured all ECGs, without user interference. RESULTS: The PQRST points were correctly detected but in two ECGs with AV block II-III. The software was not designed to detect atrial activity in atrial fibrillation (n = 9) and flutter (n = 1). In one case of atrial fibrillation, atrial activity interfered with positioning of QRS and T offsets. Regression coefficients between EClysis and CSE (software-generated and human) were above 0.95 (P < 0.0001). The confidence intervals were 95% for the slope and the intercept of the regression lines. CONCLUSIONS: The PC-based detection and analysis of PQRST points showed a high level of agreement with the CSE database reference values.
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Dota et al. (2009) conducted an observational in Normal and pathological ECGs (n=125). EClysis software vs. CSE Reference Database (Combined Median Program and manual measurements) was evaluated on Correlation of global onsets and offsets of waves with the Combined Median Program (r > 0.98, p=<0.0001). The EClysis software demonstrated a high level of agreement with the CSE database reference values for the detection of PQRST points, with regression coefficients above 0.95 (P < 0.0001).
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