Key result
Higher education linked to ~555% higher odds of adequate AF and OAC knowledge.
Why the study?
AF increases the risk of stroke and cardiovascular complications, and oral anticoagulants effectively reduce this risk, prompting investigation into patients' knowledge, attitude, and practice toward OACs.
Cross-Sectional (n=491)
No
Effect estimate: OR 6.545 (95% CI 2.863-14.963)
p-value: p=<0.001
Patients with atrial fibrillation have significant gaps in knowledge, attitude, and practice regarding oral anticoagulation, emphasizing the need for targeted patient education.
Supports targeted education for lower-educated AF patients; leaves open whether knowledge gains improve adherence or outcomes.
Background Atrial fibrillation (AF) is a common cardiac arrhythmia that increases the risk of stroke and other cardiovascular complications. Oral anticoagulants (OACs) are effective in reducing this risk. To investigate the knowledge, attitude and practice (KAP) toward OACs among patients with AF. Methods This web-based cross-sectional study was conducted at local Hospital between April 2023 and May 2023, and enrolled AF patients. Results A total of 491 valid questionnaires were collected, with 293 (59.67%) male and 73.93% resided in urban areas. The KAP scores were 4.64 ± 3.28, 21.09 ± 2.33 and 26.18 ± 2.15, respectively. Multivariate logistic regression analysis showed that junior high school [odd ratio (OR) = 0.346, 95% confidence interval (CI) = 0.145–0.825, P = 0.017], junior college/bachelor and above (OR = 6.545, 95% CI = 2.863–14.963, P < 0.001), monthly income ≥5,000 (OR = 2.343, 95% CI = 1.074–5.111, P = 0.032), never taken OACs (OR = 0.015, 95% CI = 0.004–0.059, P < 0.001), and having been diagnosed AF (6–10 months, OR = 4.003, 95% CI = 1.653–9.692, P = 0.002;over 20 months, OR = 4.046, 95% CI = 1.753–9.340, P = 0.001) were independently associated with knowledge. Knowledge (OR = 1.376, 95% CI = 1.162–1.629, P < 0.001), junior high school (OR = 0.258, 95% CI = 0.084–0.792, P = 0.018), monthly income ≥5,000 (OR = 5.486, 95% CI = 1.834–16.412, P = 0.002), and never undergone AF ablation (OR = 0.214, 95% CI = 0.097–0.471, P < 0.001) were independently associated with attitude. Knowledge (OR = 1.128, 95% CI = 1.030–1.235, P = 0.009), 70–79 years (OR = 2.193, 95% CI = 1.166–4.124, P = 0.015) and ≥80 years (OR = 4.375, 95% CI = 2.034–9.411, P < 0.001) were independently associated with proactive practice. Conclusion Patients with AF had inadequate knowledge, suboptimal attitude and inactive practice towards AF and OACs. Improving patient education, especially among those with lower education levels, enhances understanding and management of AF and OACs.
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Li et al. (2023) conducted a cross-sectional in Atrial fibrillation (n=491). Higher education level (junior college/bachelor and above) was independently associated with adequate knowledge of atrial fibrillation and oral anticoagulants (OR 6.545).
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