Key result
MitraClip provides an effective therapeutic option for patients with severe mitral valve regurgitation at prohibitive surgical risk, with optimal outcomes depending on careful patient selection based on anatomical and clinical criteria.
Why the study?
Does percutaneous edge-to-edge repair with MitraClip improve outcomes in patients with symptomatic, severe mitral valve regurgitation who are at prohibitive surgical risk?
Does percutaneous edge-to-edge repair with MitraClip improve outcomes in patients with symptomatic, severe mitral valve regurgitation who are at prohibitive surgical risk?
Answers are grounded in this paper and cite their sources.
Proper patient selection, particularly targeting A2-P2 pathology and adhering to multidisciplinary heart team evaluation, is crucial for optimizing outcomes with MitraClip therapy.
Edge-to-edge repair with the percutaneous MitraClip technology has changed the landscape for patients with symptomatic, severe degenerative mitral valve regurgitation who are at prohibitive surgical risk. While the results of randomized controlled trials of MitraClip therapy in patients with functional mitral valve regurgitation are still pending, single center experiences as well as registry data generally support the real-world application of the MitraClip therapy. In the majority of individuals treated with MitraClip, complete or near-complete relief of mitral regurgitation occurs, with results approaching the effectiveness of open surgery. This perspective summarizes the data, with a focus on current selection criteria of percutaneous MitraClip edge-to-edge repair that can optimize clinical outcomes.
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Gössl et al. (2018) conducted a review in Severe mitral valve regurgitation. MitraClip was evaluated. MitraClip provides an effective therapeutic option for patients with severe mitral valve regurgitation at prohibitive surgical risk, with optimal outcomes depending on careful patient selection based on anatomical and clinical criteria.
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