Key result
True myxomas of the lateral skull base are extremely rare, with only 4 cases meeting histopathologic criteria, typically presenting with facial palsy and mastoid cavity involvement.
Case Report (n=4)
True myxoma should be considered in the differential diagnosis of lateral skull base lesions, with radical surgery as the treatment of choice.
Supports including true myxoma in lateral skull base differentials; extends sparse histopathologic data without guiding management.
OBJECTIVE: To evaluate the clinical features and incidence of true myxomas affecting the lateral skull base. MATERIAL AND METHODS: Illustrative case report and review of the relevant literature. Included are all reports of myxomas according to the histopathologic definition of Stout. RESULTS: Despite nine case reports, only four patients matched the histopathologic criteria of a true myxoma growing in the lateral skull base. Facial palsy occurred in three adults with additional otalgia in one and progressive hearing loss (HL) in another patient. Our patient initially presented with signs of recurrent otitis media. The mastoid cavity was involved in all patients. CONCLUSION: Differential diagnosis of lesions occurring in the lateral skull base should include true myxoma. Correct diagnosis should be based on immunohistopathology to rule out malignant tumors. Radical surgery is the treatment of choice, but surgeons should respect vital structures and esthetic consequences.
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Windfuhr et al. (2004) conducted a case report in True myxomas affecting the lateral skull base (n=4). Radical surgery was evaluated on Clinical features and incidence of true myxomas affecting the lateral skull base. True myxomas of the lateral skull base are extremely rare, with only 4 cases meeting histopathologic criteria, typically presenting with facial palsy and mastoid cavity involvement.
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