Key result
Higher intensity physical activity is linked to lower arterial stiffness versus inactivity regardless of weekly pattern.
Why the study?
The study was conducted to examine the associations of the amount and pattern of higher intensity physical activity with arterial stiffness.
Does higher intensity physical activity, regardless of pattern, reduce arterial stiffness in adults?
Observational (n=1,699)
Does higher intensity physical activity, regardless of pattern, reduce arterial stiffness in adults?
Effect estimate: Beta -0.46 (95% CI -0.71 to -0.21)
Higher intensity physical activity is associated with lower arterial stiffness regardless of whether it is performed regularly or in a 'weekend warrior' pattern, particularly in patients with type 2 diabetes.
May support emphasizing higher-intensity activity in prevention counseling; leaves open causality and hard-outcome effects.
We examined the associations of the amount and the pattern of higher intensity physical activity with arterial stiffness. Data from The Maastricht Study (n=1699; mean age: 60±8 years, 49.4% women, 26.9% type 2 diabetes (T2DM)) were used. Arterial stiffness was assessed by carotid-to-femoral pulse wave velocity (cfPWV). The amount (hours/day) and pattern of higher intensity physical activity were assessed with the activPAL3®. Activity groups were: inactive (<75min/week), insufficiently active (75-150min/week), weekend warrior (>150min/week in ≤2 sessions), and regularly active (>150min/week in ≥3 sessions). After full adjustment, higher intensity physical activity was associated with lower cfPWV (amount: -0.35[-0.65;-0.05], insufficiently active: -0.33[-0.55;-0.11]; weekend warrior: -0.38[-0.64;-0.12] and regularly active: -0.46[-0.71;-0.21] (reference: inactive)). These associations were stronger in those with T2DM. Participating in higher intensity physical activity was associated with lower cfPWV, regardless of the weekly pattern, and may be an important strategy to reduce CVD risk, particularly in T2DM.
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Vandercappellen et al. (2020) conducted an observational in Arterial stiffness (n=1,699). Higher intensity physical activity vs. Inactive (<75min/week) was evaluated on Arterial stiffness assessed by carotid-to-femoral pulse wave velocity (cfPWV) (Beta -0.46, 95% CI -0.71 to -0.21). Higher intensity physical activity was associated with lower arterial stiffness compared to inactivity, regardless of weekly pattern (e.g., regularly active difference -0.46; 95% CI -0.71 to -0.21).
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