Why the study?
Does the choice of statin treatment guideline affect the effectiveness and efficiency of preventing coronary heart disease deaths in the Canadian population?
Population
6760 men and women aged 20-74 years from the Canadian Heart Health Survey with physical measurements…
Comparison
Statin treatment recommendations from six… vs Comparison among the six different guidelines.
Follow-up
5 years (modelled)
Authors
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Adopting New Zealand statin thresholds may optimize Canadian prevention efficiency; extends cross-national guideline comparisons.
Does the choice of statin treatment guideline affect the effectiveness and efficiency of preventing coronary heart disease deaths in the Canadian population?
The New Zealand statin guidelines are the most efficient for the Canadian population, avoiding nearly as many deaths as the most effective guidelines while recommending treatment for significantly fewer people.
Manuel et al. (2006) studied Coronary heart disease (n=6,760). Statin treatment guidelines was evaluated on Number of people recommended for treatment, potential number of deaths from coronary heart disease avoided, and number needed to treat. The New Zealand statin guidelines were the most efficient for the Canadian population, potentially avoiding 14,700 deaths over 5 years while recommending treatment to only 12.9% of people.
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