Experiences of Scalp Cooling Therapy in Neoadjuvant Chemotherapy for Breast Cancer: An Aspect of Supportive Care Based on Patients’ Free-text Responses

January 1, 2026Palliative Care ResearchOpen Access

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Key Points

This research aims to explore the experiences and perceptions of patients undergoing scalp cooling therapy during neoadjuvant chemotherapy for breast cancer.
Qualitative content analysis of survey responses from breast cancer patients undergoing neoadjuvant chemotherapy with scalp cooling
Involved both multiple-choice and free-text responses
Sample included 22 consenting participants from an initial group of 50
Identified categories include 'environmental adjustments', 'physical discomfort and conflict over hair loss prevention', 'cost implications for continuation', and 'uncertainty regarding cooling effectiveness'
Median patient age was 48.5 years
Physical discomfort included jaw pain and cold sensations, affected by environmental adjustments and healthcare provider involvement in pain management.

Qualitative analysis reveals patient experiences and challenges with scalp cooling during chemotherapy, suggesting supportive care benefits.

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Nakao et al. (2026) studied this question.

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