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May 28, 2026Journal of SurgeryOpen Access

Nissen Versus Toupet Fundoplication in GERD: Comparable Long-term Outcomes with Distinct Functional Profiles

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Authors

FLFernando LisboaGDGabriel DantasAAAngelo Alves

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Overview

Randomized trial compares reflux control and dysfunction profiles in GERD surgeries, suggesting individualized approaches.

Key Points

  • To compare the long-term efficacy and functional outcomes of Nissen and Toupet fundoplication surgeries for GERD.
  • Systematic review conducted following PRISMA guidelines
  • Included randomized controlled trials and cohort studies published from 2002 to 2025
  • Primary outcomes: postoperative dysphagia and reflux control; secondary outcomes: PPI use, quality of life, patient satisfaction, reoperation rates.
  • Both techniques effectively controlled reflux with comparable long-term outcomes.
  • Nissen fundoplication showed higher lower esophageal sphincter pressure but did not yield superior clinical outcomes.
  • Toupet fundoplication had fewer early dysphagia cases and better esophageal motility preservation.

Cite This Study

Lisboa et al. (2026) studied this question.

synapsesocial.com/papers/6a17db6f3fad632b0f9d83b1https://doi.org/10.11648/j.js.20261403.12
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