Pregnancy outcome in Saudi women with systemic lupus erythematosus

Background: The aim of the study was to assess the clinical characteristics of our systemic lupus erythematosus (SLE) patients at the time of pregnancy as well as their outcomes. Materials and Methods: A retrospective study for 86 pregnancies of SLE patients from 2019 to 2021 in King Fahad Medical City was performed. Descriptive analysis was used. Results: A total of 86 patients were included. Seventy-four (86%) patients have disease for more than 6 months. Preeclampsia was diagnosed in 12 patients; premature delivery occurred in 13 patients (15.1%), and intrauterine growth retardation occurred in 11 patients (12.7%). Twenty-six (30%) patients had abortions and three patients had a stillbirth. Twenty-six (30%) patients had cesarean sections and 35 (40%) patients delivered with normal spontaneous delivery. Seven patients (8.14%) had disease flares during pregnancy and only one death occurred. Conclusions: Our study provides data on clinical, laboratory, therapeutic and outcome features of pregnancies of Saudi lupus patients.