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May 20, 2019Journal of Magnetic Resonance Imaging53 citationsOpen Access

Quantitative cardiac MRI

ASAndreas SeraphimKKKristopher KnottJAJoão B. Augusto

Key Result

Quantitative cardiac MRI techniques, including parametric mapping and perfusion, are emerging as essential tools for the early detection, monitoring, and risk stratification of cardiovascular diseases.

Structured PICO

P
Population
Patients with suspected heart disease
I
Intervention
Quantitative cardiac MRI techniques

Quantitative cardiac MRI is an essential tool for assessing cardiac function and tissue characterization, with emerging applications in machine learning and personalized disease management.

Limitations

  • Different imaging modalities yield different results for cardiac volumes and function.
  • Lack of uniformly accepted conventions for measuring trabeculae and papillary muscles.
  • Manual contouring variability persists despite quality control and training.
  • Standardization is needed across different vendors, pulse sequences, and software for strain and mapping.
  • Quantitative perfusion techniques often require onerous post-processing, impeding widespread clinical adoption.

Abstract

Cardiac MRI has become an indispensable imaging modality in the investigation of patients with suspected heart disease. It has emerged as the gold standard test for cardiac function, volumes, and mass and allows noninvasive tissue characterization and the assessment of myocardial perfusion. Quantitative MRI already has a key role in the development and incorporation of machine learning in clinical imaging, potentially offering major improvements in both workflow efficiency and diagnostic accuracy. As the clinical applications of a wide range of quantitative cardiac MRI techniques are being explored and validated, we are expanding our capabilities for earlier detection, monitoring, and risk stratification of disease, potentially guiding personalized management decisions in various cardiac disease models. In this article we review established and emerging quantitative techniques, their clinical applications, highlight novel advances, and appraise their clinical diagnostic potential. Level of Evidence: 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2020;51:693-711.

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Cite This Study

Seraphim et al. (2019) conducted a review in Cardiovascular disease. Quantitative Cardiac MRI was evaluated. Quantitative cardiac MRI techniques, including parametric mapping and perfusion, are emerging as essential tools for the early detection, monitoring, and risk stratification of cardiovascular diseases.

synapsesocial.com/papers/6a180b2a3aabde875b133cffhttps://doi.org/10.1002/jmri.26789
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