In this issue, Matsumoto et al. ([1][1]) report that histamine exocytosed from brain mast cells (MCs) after activation by antigenic cross-linking of the high affinity IgE receptor (FceRI) acts via Hl receptors at the hypothalamus to elicit corticotropin-releasing factor (CRF). These findings reveal
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Gurish et al. (2001) studied this question.
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